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The link between BCL2 proteins and Parkinson's disease

We hypothesize that the machinery directly responsible for executing cell death is composed of a precisely calibrated array of BCL2 proteins. Paradoxically, these BCL2 proteins, required for proper development of the dopaminergic system, may also cause vulnerability of this system in the adult, as these BCL2 proteins have recently been linked to Parkinson's disease. In addition to the intriguing possibility of finding useful biomarkers for predicting later neurodegeneration, further investigation of these factors could open new paths for treating Parkinson's disease.
Publication
Journal:
Molecular Medicine
Year of Publication:
2014
Volume:
20
Issue:
6
Date Published:
09/2014
Caeiro, P., Costa, T., Alves, R., & Lopes, S. (2014). The link between BCL2 proteins and Parkinson's disease. Molecular Medicine, 20(6). http://doi.org/Omibee Research (Original work published September 2014)
Identifiers
ISSN:
1234
ISBN Number:
5678
Accession Number:
9012
Call Number:
3456
Other Numbers:
7890
Locators
URL:
https://research.omibee.com
DOI:
Omibee Research
Alternative titles
Original Publication:
The link between BCL2 proteins and Parkinson's disease
Alternate Journal:
The link between BCL2 proteins and Parkinson's disease
Short Title:
BCL2 proteins and Parkinson's disease

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